British Air Force Typhoon jets have operated alongside French warplanes in a combined operation on an hidden munitions depot in Syria operated by the IS group, as stated by the UK's MoD.
The location, located using reconnaissance, was believed to be storing arms and explosives, the statement said, and was located in mountainous terrain just to the north of the historic site of Palmyra in Syria's central region.
"Our fighter planes used Paveway IV guided bombs to hit a number of entry passages leading to the site... preliminary assessments are that the target was engaged successfully," the ministry announced.
There was no sign of any civilian impact in the operation late on Saturday and each participating jet returned safely, the defence officials confirmed.
The Typhoon FGR4s were backed up by a Voyager aerial refuelling aircraft.
Daesh - also known as ISIS - established extremist governance over parts of Syria and Iraq prior to its 2019 collapse.
"This strike shows British leadership, and commitment to stand shoulder to shoulder with our allies, to eradicate any resurgence of IS and their harmful and extremist ideologies in the area," the British Defence Secretary the minister said.
RAF aircraft have performed surveillance missions over Syria to "forestall any attempted resurgence" of the group subsequent to its defeat at the climactic battle in Baghuz in the year 2019, the authorities noted.
"I must thank the personnel of British forces participating in this strike for their skill and their valour," he added. "Including them were numerous British troops on duty over the holidays. This action, to eliminate terrorist threats who pose a risk to our way of life, demonstrates how British military are prepared to act, all year round, ensuring Britain's security domestically and influential overseas."
In December, the US military conducted what it called a "large-scale strike" on IS targets in the country, after an attack claimed the lives of two US servicemembers and a civilian linguist in Palmyra.
The UN says IS still boasts an estimated 5,000 to 7,000 militants in Syria and Iraq.
